Company Details

  • Zhiyuan Biotchnology

  •  [Shandong,China]
  • Business Type:Manufacturer
  • Main Mark: Africa , Americas , Asia , Caribbean , Europe , North Europe , Oceania , West Europe , Worldwide , East Europe , Middle East
  • Exporter:51% - 60%
  • Certs:ISO9001, ISO14001, FDA
  • Description:Hydroxypropyl Cyclodextrin 128446-35-5 HPBCD,Hydroxypropyl Beta Cyclodextrin Uses,Hydroxypropyl Beta Cyclodextrin Molecular Weight
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Zhiyuan Biotchnology

Hydroxypropyl Cyclodextrin 128446-35-5 HPBCD,Hydroxypropyl Beta Cyclodextrin Uses,Hydroxypropyl Beta Cyclodextrin Molecular Weight

Home > Products > Hydroxypropyl Cyclodextrin Derivatives > Hydroxypropyl Beta Cyclodextrin > Pharmaceutical expicent hydroxypropyl beta cyclodextrin

Pharmaceutical expicent hydroxypropyl beta cyclodextrin

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    Payment Type: L/C,T/T,D/P,Paypal
    Incoterm: FOB,CFR,CIF
    Min. Order: 1 Bag/Bags
    Delivery Time: 1 Days

Basic Info

Model No.: ZY-001

Classification: Organic Analytical Reagents

Specific Usage: For Biological Purpose

Content: Standard

Usage: Laboratory Reagents, Analytical Reagents, Teaching Reagents

Source: Dry Powder

Habit Appellation: Chemical Medicine

Application: Industry, Scientific Research, Health, Environmental Protection, Agriculture

Property: Organic Reagent

Grade: CP

Additional Info

Packaging: 10kg/drum

Productivity: 5000KGS

Brand: Zhiyuan

Transportation: Ocean,Land

Place of Origin: China

Supply Ability: 5000kgs

Certificate: ISO9001

Product Description

Main Function of Hydroxypropyl Beta Cyclodextrin:

hydroxypropyl beta cyclodextrin HPBCD

1.Improving the solubility of drugs.Insoluble drugs including Chinese herbal medicines might be turned into injections by the derivatives of cyclodextrins
2.Inproving the bioavailability of drugs.For example,effectively control release oral dosing of injection of 5-fuorocarbamidopyrimidine might be prepared with an improved bioavailability,which might bring in a decreasing of the dosage but an increasing of the curative effect.On the other hand,an injection could be worked on the patients who haven't any go-aheadism.
3.Adjusting or controlling the releasing of the drugs.For example,lasting effective dosings of VA,VE,VD,VK,testosterone and progesterone etc might be made with an improved stability.
4.Decreasing the toxicities of the drugs.For example,to decrease the haemocylolysis of the drugs.The stimulating to eyes or nasal cavities of the related drugs cold also be decreased.
5.Improving the stabilities of the drugs.For example,to prevent the volatilization,sublimation,oxidation decomposition etc.
6. Concealing or rectifying the badness odor of testing.
7.Inproving the synthesis effects as well as qualities of the drugs by chiral selective catalysis of cyclodextrin derivatives.It is very important for a chiral structure in drugs.
8.Constructing stational chiral phases for the separation of isomers of drugs.
9.Exploring molecular probes for examining differentiation of gene etc.
10.Looking for new drugs or new coordination materials by more proper modifications of cyclodextrions.
11.The recent work shows that HP beta CD etc could also accelerate the permeable absorption of the drugs of Testosterne etc.
12.Cyclodextrin derivatives not only could play an important role in drugs and related field,but also could play an important role in cosmetics,foods and spices etc based on the structures of cyclodextrin derivatives.

128446-35-5



Name: hydroxypropyl- beta-cyclodextrin

Other name : hydroxypropyl betadex ;

2-hydroxypropyl-beta-cyclodextirn ;

hydroxypropyl-β-cyclodextrin .

Abbreviation : HPBCD

CAS: 128446-35-5; 94035-02-6; 136019-12-0

EINECS: 420-920-1

Molecular formula :C42H70-nO35(C3H8O2)n

Molecular weight: 1134.98+58n

Solubility(in 100cm3 solvent, at 25℃) : water: >180 g

Methanol: >33g

DMSO: >33g

Qaulity : Pharma grade / food grade / cosmetics grade / industry grade

Standard : USP38/ EP8.0 / CP2015

Package: 500g/bag , 2kg/bag, 10kg/drum , 20kg/drum or customized

Use : medical \ food \ chemical \ cosmetic \ other industries

Specification :

ITEMS

SPECIFICATION(USP38)

RESULTS

Appearance

white powder, insipid, innocent

Qualify

Assay

≥98%

99.5%

Degree of Substitution

2.8-10.5

5.5

Clarity of solution

50%(w/v) water solution is clear

clear

Identification(IR)

same absorption bands with USP Hydroxypropyl Betadex RS

Qualify

Loss on Drying

≤10%

4.5%

Conductivity

10%(w/v) water solution ≤200µS/cm

70

Propylene oxide

≤1ppm

<0.18ppm

Propylene glycol

≤2.5%

0.05%

Sum of Other Impurities

≤1%

0.51%

Betadex

≤1.5%

0.39%

Residue on Ignition

≤0.2%

0.09%

Heavy Metal

≤20ppm

<10ppm

chloride

≤0.05%

<0.05%

Bacterial endotoxins

≤25EU/g

<20EU/g

TAMC(cfu/g)

≤1000

80

TYMC(cfu/g)

≤100

30

Salmonella/E. Coli (cfu/g)

Absent

Absent

Storage: at room temperature, in tightly closed container.

Applications:

Hydroxypropyl-β-cyclodextrin (HP-β-CD) is one of the most widely used cyclodextrin derivatives in current scientific researches and industry applications. It mainly used in food, pharmaceutical and cosmetics industries.

(1). In medicine field

Hydroxypropyl Beta Cyclodextrin can increase the solubility of the medicine and biological availability, also add up the good effect and decrease the dose.

Meanwhile, it control or adjust the reactive speed, lower the drug toxicity and enhance the stability of drugs.Moreover, It is for oral solution with the highest safety.



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Product Categories : Hydroxypropyl Cyclodextrin Derivatives > Hydroxypropyl Beta Cyclodextrin

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